The Basilica of Saint Nicholas (Dutch: Basiliek van de Heilige Nicolaas) is located in the Old Centre district of Amsterdam, Netherlands, very close to Amsterdam's main railway station. It is the city's primary Roman Catholic church.

The church is built on a previously urban site, necessitating a northwest-southeast axis to be adopted, rather than the standard east-west axis. It lies between the street, Prins Hendrikkade, and the canal, Oudezijds Kolk.