The City Hall (Dutch: Stadhuis ) of Antwerp, Belgium, stands on the western side of Antwerp's Grote Markt ("Great Market Square"). Erected between 1561 and 1565 after designs made by Cornelis Floris de Vriendt and several other architects and artists, this Renaissance building incorporates both Flemish and Italian influences. The Stadhuis is listed as one of the Belfries of Belgium and France, a UNESCO World Heritage Site.

In the 16th century Antwerp became one of the busiest trading ports and most prosperous cities in Northern Europe. The municipal authorities wished to replace Antwerp's small medieval town hall with a more imposing structure befitting the prosperity of the great port city. Antwerp architect Domien de Waghemakere drafted a plan (c. 1540) for a new building in a style typical of the monumental Gothic town halls of Flanders and Brabant.