Mühlendamm (Mill Dam) is a major thoroughfare in the central Mitte district of Berlin, Germany. It runs from the historic Cölln and Fischerinsel quarters to the Molkenmarkt square of Alt-Berlin via the Mühlendammbrücke (Mill Dam Bridge) crossing the Spree river. Named after several watermills at the site, a historic causeway was first laid out at this location about 1200 and became the nucleus of the late medieval city foundation. The current prestressed concrete bridge was built in 1968. It is part of an east–west road link to Berlin's city centre and the Bundesstraße 1 highway.
The bridge links Gertraudenstraße, Spittelmarkt and Leipziger Straße in the southwest with the Alexanderplatz area in the northeast. It thereby is part of the main east-west road connection in Berlin's historic city centre, beside the parallel route of Unter den Linden, Schloßplatz and Karl-Liebknecht-Straße in the north. East of the bridge is a large lockage, called Mühlendammschleuse, part of the Spree-Oder waterway.
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