The Berklee Performance Center is a 1,215-seat theatre located on Massachusetts Ave. in the Back Bay area of Boston, Massachusetts. It is the largest theatre space on the Berklee College of Music campus and is used primarily for college-affiliated activities. Presenters from outside the Berklee community also rent it for performances of all kinds. In 2009, the Berklee Performance Center hosted a total of 200 events.

In 1972, Berklee purchased the Fenway Theatre at 136 Massachusetts Avenue. The 1915 movie palace, designed by Thomas Lamb, was renovated and reopened as the Berklee Performance Center in 1976.