Roe & Co Distillery is an Irish whiskey distillery established in 2019. It is located on Thomas Street, Dublin, Ireland near the Guinness' St. James' Gate brewery.

The Thomas Street Distillery, run by the Roe Family, was once the largest in the Britain and Ireland, with an output of two million gallons per annum at its peak. It was located opposite Guinness' St. James' Gate brewery. After the distillery was closed in 1926, some of its buildings were purchased and incorporated into the Guinness Brewery.