Durham, United States

Durham ( DURR-əm) is a city in the U.S. state of North Carolina and the county seat of Durham County. Small portions of the city limits extend into Orange County and Wake County. With a population of 283,506 in the 2020 census, Durham is the 4th-most populous city in North Carolina, and the 74th-most populous city in the United States. The city is located in the east-central part of the Piedmont region along the Eno River. Durham is the core of the four-county Durham-Chapel Hill Metropolitan Area, which had a population of 649,903 at the 2020 census. The Office of Management and Budget also includes Durham as a part of the Raleigh-Durham-Cary Combined Statistical Area, commonly known as the Research Triangle, which had a population of 2,043,867 at the 2020 census.

A railway depot was established in 1849 on land donated by Bartlett S. Durham, the namesake of the city. Following the American Civil War, the community of Durham Station expanded rapidly, in part due to the tobacco industry. The town was incorporated by act of the North Carolina General Assembly, in April 1869. The establishment of Durham County was ratified by the General Assembly 12 years later, in 1881. It became known as the founding place and headquarters of the American Tobacco Company. Textile and electric power industries also played an important role. While these industries have declined, Durham underwent revitalization and population growth to become an educational, medical, and research center.