Guangzhou (UK: , US: ; simplified Chinese: 广州; traditional Chinese: 廣州; pinyin: Guǎngzhōu; Cantonese pronunciation: [kʷɔ̌ːŋ.tsɐ̂u] or [kʷɔ̌ːŋ.tsɐ́u] (listen); Mandarin pronunciation: [kwàŋ tʂóu] (listen)), also known as Canton and alternatively romanized as Kwongchow or Kwangchow, is the capital and the largest city of Guangdong province in southern China. Located on the Pearl River about 120 km (75 mi) north-northwest of Hong Kong and 145 km (90 mi) north of Macau, Guangzhou has a history of over 2,200 years and was a major terminus of the maritime Silk Road, and continues to serve as a major port and transportation hub, as well as one of China's three largest cities. For a long time the only Chinese port accessible to most foreign traders, Guangzhou was captured by the British during the First Opium War. No longer enjoying a monopoly after the war, it lost trade to other ports such as Hong Kong and Shanghai, but continued to serve as a major transshipment port. Due to a high urban population and large volumes of port traffic, Guangzhou is classified as a Large-Port Megacity, the largest type of port-city in the world. Due to worldwide pandemic-related restrictions on traveling in 2020, Guangzhou Baiyun International Airport, the major airport of Guangzhou, became the world's busiest airport by passenger traffic.

Guangzhou is at the heart of the most-populous built-up metropolitan area in the world, which extends into the neighboring cities of Foshan, Dongguan, Zhongshan, Shenzhen and part of Jiangmen, Huizhou, Zhuhai and Macao, forming the largest urban agglomeration on Earth with approximately 65,594,622 residents and part of the Pearl River Delta Economic Zone. Administratively, the city holds subprovincial status and is one of China's nine National Central Cities. In the late 1990s and early 2000s, nationals of sub-Saharan Africa who had initially settled in the Middle East and Southeast Asia moved in unprecedented numbers to Guangzhou in response to the 1997/98 Asian financial crisis. The domestic migrant population from other provinces of China in Guangzhou was 40% of the city's total population in 2008. Together with Shanghai, Beijing and Shenzhen, Guangzhou has one of the most expensive real estate markets in China. As of the 2020 census, the registered population of the city's expansive administrative area was 18,676,605 individuals (up to 47% from the previous census in 2010) whom 16,492,590 lived in 9 urban districts (all but Conghua and Zengcheng).