Boon Lay Bus Interchange is an air-conditioned bus interchange located in Jurong West Central, in the western part of Singapore. It is situated within Jurong Point and integrated with the nearby Boon Lay MRT station. This interchange serves a variety of passengers, including those from Nanyang Technological University, Jurong Industrial Estate and Tuas Industrial Estate. The interchange has been among the largest and busiest bus interchanges in Singapore, handling 31 services in the past until a few services were amended to the newer Joo Koon Bus Interchange in 2015.

Boon Lay Bus Interchange began operating on 1 July 1990 with services that used to terminate at the former Jurong Bus Interchange at Jurong Port Road and Jurong East Bus Interchange being re-routed to terminate there. That time, the Jurong West extension and Tuas Industrial area was still largely under development. As both areas are undergoing development, more bus services were introduced and by the early 2000s, there were about 30 bus services terminating at the interchange.