The National Museum of Art, Palacio Diez de Medina is a museum in the city of La Paz, Bolivia. It has an important permanent collection of colonial paintings, including canvases by Melchor Pérez de Holguín, a painter 16th century and those of Gregorio Gamarra, a 17th-century painter.

The museum is located right in front of the main square of the city of La Paz, Plaza Murillo, specifically at the intersection of the pedestrian promenade Calle Comercio and Calle Socabaya.