Nakhon Phanom (นครพนม) is a city and province in Isaan.
Nakhon Phanom is in the northeastern region of Thailand, approximately 734 km northeast of Bangkok and 378 km southwest of Hanoi, Vietnam. It borders Lao PDR's Khamoun Province, Tha Khaek District. Nakhon Phanom was the site of a US base during the Vietnam War, housing the 56th Air Commando Wing, based at Nakhon Phanom Royal Thai Air Force Base. Its mission was search and rescue and interdiction of the Ho Chi Minh Trails in Laos 48 km to the east.