Newbury Lock is a lock on the Kennet and Avon Canal in the town centre of Newbury, in the English county of Berkshire. It has a rise/fall of 3 ft 6 in (1.07 m), and is situated just upstream of Newbury Bridge.

The lock is a grade II listed structure. It has brick walls that are capped with Bath Stone and which are wider at the top than at the base in an attempt to counteract frost damage. It was built in 1796, as part of the construction of the Kennet and Avon Canal linking Newbury and Bath. The canal was built under the supervision of John Rennie.