The Sorbonne ( sor-BON, US also sor-BAWN, French: [sɔʁbɔn] (listen)) is a building in the Latin Quarter of Paris which from 1253 onwards housed the College of Sorbonne, part of one of the first universities in the Western world, later renamed to University of Paris and commonly known as "the Sorbonne". Today, it continues to house the successor universities of the University of Paris, such as Panthéon-Sorbonne University, Sorbonne University, Sorbonne Nouvelle University and Paris City University, as well as the Chancellerie des universités de Paris. Sorbonne Université is also now the university resulting from the merger on 1 January 2018 of Paris 6 UPMC and Paris 4 Sorbonne.

The college was founded in 1253 by Robert de Sorbon. Louis IX of France confirmed the foundation in 1257. It was one of the first significant colleges of the medieval University of Paris. The library was among the first to arrange items alphabetically according to title. The university predates the college by about a century, and minor colleges had been founded already during the late 12th century. During the 16th century, the Sorbonne became involved with the intellectual struggle between Catholics and Protestants. The University served as a major stronghold of Catholic conservative attitudes and, as such, conducted a struggle against King Francis I's policy of relative tolerance towards the French Protestants, except for a brief period during 1533 when the University was placed under Protestant control. The Sorbonne, acting in conjunction with the Catholic Church, condemned 500 printed works as heretical between 1544 and 1556.