The Smíchov – Hostivice railway line or Prague Semmering is a railway line in the Czech Republic. The line was built in 1868–1872 by the Buštěhrad Railway company (Czech: Buštěhradská dráha, German: Buschtiehrader Eisenbahn) as part of its connection between Prague and Chomutov.
The line was opened for cargo transport on 3 July 1872. It was used to transport coal and wood to Prague. Transport of passengers followed on 16 September 1872.
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