Sisaket (ศรีสะเกษ, sometimes Si Saket) is a town and a province in Isaan, Thailand.
With a long history, the area around Sisaket has had a strong culture and a prosperous economy since the Khmer era over one thousand years ago. Moreover, many ethnic tribes settled here such as the Suay, Lao, Khmer, and Yer. Sisaket became a town in 1759 during Ayuthaya period. In the reign of King Rama V, or around a century ago, the town moved to its present location.