Tokushima Prefecture (徳島県, Tokushima-ken) is a prefecture of Japan located on the island of Shikoku. Tokushima Prefecture has a population of 728,633 (1 October 2019) and has a geographic area of 4,146 km² (1,601 sq mi). Tokushima Prefecture borders Kagawa Prefecture to the north, Ehime Prefecture to the west, and Kōchi Prefecture to the southwest.

Tokushima is the capital and largest city of Tokushima Prefecture, with other major cities including Anan, Naruto, and Yoshinogawa. Tokushima Prefecture is located on the Kii Channel, connecting the Pacific Ocean and Seto Inland Sea, across from Wakayama Prefecture on the Kii Peninsula of the island of Honshu. Tokushima Prefecture is connected to Awaji Island across the Naruto Strait by the Ōnaruto Bridge as part of the Kobe-Awaji-Naruto Expressway, connecting the prefecture to the city of Kobe and the San'yō Expressway on Honshu.

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