The Palazzo Michiel Dalle Colonne is a Baroque style palace located on the northern bank of the Grand Canal in the sestiere of Cannaregio in Venice, Italy. It is one building south of the junction of Rio del Santissimi Apostoli with Grand Canal, next to the Palazzo Michiel del Brusà and across the Canal from the Rialto Mercato and the Campo della Pescaria. The palace is also referred to as Palazzo Michiel Dalle Colonne a Santa Sofia.
The present facade is mainly due to reconstructions of the original Gothic-Byzantine palace during the 17th and 18th-centuries, the most important rebuilding was by the architect Antonio Gaspari (1656-1723). The palace had many owners during the centuries including the Grimani and Zeno families.
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